Somnomed products research and development

SomnoMed® investoi ennen näkemättömän korkealla tasolla kliiniseen tutkimukseen ja tuotekehittelyyn. Näin voidaan taata, että tuotteiden käyttömukavuus, laatu ja vaikutus ovat kehityksen kärjessä.

Tällä hetkellä on jo saatavilla 16 julkaisua uniapneakiskojen (COAT) tehosta ja vaikutuksesta verrattuna CPAP:hen. Näissä tutkimuksissa on etupäässä verrattu AHI:n vähenemistä CPAP:in ja kiskojen välillä (COAT).

Näiden tutkimusten tärkeimmät tulokset ovat:

  • Ei eroa uniapnean hoidon onnistumisessa kahden vuoden kuluttua
  • Kisko on suosituin hoitomuoto
  • Kiskon kohdalla hoito-ohjelmaa noudatetaan paremmin
  • Verrattaessa verenpainearvoja kisko on samanvertainen CPAP:in kanssa
  • Aamuiset verenpainearvot ovat laskeneet kiskon ja CPAP:in kohdalla

“Health Outcomes of Continuous Positive Airway Pressure versus Oral Appliance Treatment for Obstructive Sleep Apnea – A Randomized Controlled Trial” Craig L. Phillips, Ronald R. Grunstein, M. Ali Darendeliler, Anastasia S. Mihailidou, Vansantha K. Srinivasan, Brendon J. Yee, Guy B. Marks, and Peter A. Cistulli

 

Yrityksen tarkoituksena on järjestää myös tulevaisuudessa tutkimuksia SomnoDent-tuotteiden vaikutuksesta, käyttömukavuudesta ja laadusta

Yleiskatsaus tärkeimmistä kliinisistä tutkimustuloksista

Biao Zeng, MD, PhD, Andrew T. Ng, MBBS, Jin Qian, MBiomedEng, Peter Petocz, PhD, M. Ali Darendaliler, PhD, Peter A Cistulli, MBBS, PhD SLEEP 2008; 31 (4): 543 – 547. Centre for Sleep Health & Research, Department of Respiratory Medicine, Royal North Shore Hospital, University of Sydney, Australia.

A Hoekema PhD thesis, University Medical Centre Groningen Department of Oral and Maxillofacial Surgery. pp 110 (2007)

Chan AS, Lee RW, Cistulli PA
CHEST. 2007 Aug; 132(2): 693-9.
Centre for Sleep Health and Research, Royal North Shore Hospital, St Leonards NSW 2065, Australia.

Zeng B, Ng AT, Darendeliler MA, Petocz P, Cistulli PA.
Am J Respir Crit Care Med. 2007 Apr 1;175(7):726-30.
Centre for Sleep Health and Research, Department of Respiratory Medicine, Royal North Shore Hospital, University of Sydney, Sydney, Australia.

Susanne Schwarting & Ulrich Huebers & Markus Heise & Joerg Schlieper & Andreas Hauschild
Published online: 27 April 2007 # Springer-Verlag 2007
A position paper of the German Society of Dental Sleep Medicine (Deutsche Gesellschaft Zahnaerztliche Schlafmedizin, DGZS)

Lim J, Lasserson TJ, Fleetham J, Wright J.
Cochrane Database Syst Rev. 2006 Jan 25
Royal Surrey County Hospital, Guildford, Surrey, UK.

Kushida CA; Morgenthaler TI; Littner MR et al.
An American Academy of Sleep Medicine Report —AASM Practice Parameters. An Update for 2005. SLEEP 2006; 29(2): 240-243

Edmund C. Rose1, Martin Germann2, Stephan Sorichter2, Irmtrud E. Jonas1
Department of Orthodontics, University of Freiburg i. Br., Germany,
Department of Pneumology, Sleep Laboratory, University of Freiburg
English version revised by Carol Cürten, Freiburg/Br. Received: July 2, 2004; accepted: September 6, 2004

Gotsopoulos H, Kelly JJ, Cistulli PA.
Sleep. 2004 Aug 1;27(5):934-41.
Department of Respiratory & Sleep Medicine, St George Hospital, The University of New South Wales, Sydney Australia.

Ng AT, Gotsopoulos H, Qian J, Cistulli PA.
Am J Respir Crit Care Med. 2003 Jul 15;168(2):238-41
Department of Respiratory Medicine, St. George Hospital, Belgrave Street, Kogarah, NSW 2217, Australia.

Andrew J. Pitsis, M. Ali Darendeliler, Helen Gotsopoulos, Peter Petocz and Peter A. Cistulli
Am. J. Respir. Crit. Care Med. 2002 Sep 15;166 (6): 860-4
Department of Respiratory Medicine, Centre for Sleep Disorders and Respiratory Failure, St. George Hospital, University of New South Wales, Kogarah; Discipline of Orthodontics, Faculty of Dentistry, University of Sydney; and Department of Mathematical Sciences, University of Technology, Sydney, New South Wales, Australia

Randerath WJ, Heise M, Hinz R, Ruehle KH. Klinik Ambrock, Hagen, CHEST. 2002 Aug;122, Germany.

Walker-Engström ML, Tegelberg A, Wilhelmsson B, Ringqvist I.
CHEST. 2002 Mar;121(3):739-46.
Center for Clinical Research, Central Hospital, Västerås, Uppsala University, Sweden.

Helen Gotsopoulos, Carol Chen, Jin Qian and Peter A. Cistulli
Am. J. Respir. Crit. Care Med., Vol 166. pp. 743-748, (2002) © 2002 American Thoracic Society
Department of Respiratory Medicine, Centre for Sleep Disorders and Respiratory Failure, St. George Hospital, University of New South Wales, Kogarah, Australia

Atul Mehta, Jin Qian, Peter Petocz, M. Ali Darendeliler, And Peter A. Cistulli
Am. J. Respir. Crit. Care Med., Volume 163, Number 6, May 2001, 1457-1461
Centre for Sleep Disorders and Respiratory Failure, Department of Respiratory Medicine, St George Hospital, University of New South Wales, Discipline of Orthodontics, Faculty of Dentistry, University of Sydney, and School of Mathematical Sciences, University of Technology, Sydney, Australia

Cistulli PA, Palmisano RG, Poole MD.
SLEEP. 1998 Dec 15;21(8):831-5
Centre for Sleep Disorders & Respiratory Failure, St George Hospital, NSW, Australia.